The 32-year-old, who won a gold medal at the Beijing Olympics in 2008, has said that a second loss to Caleb Truax would mean he would retire.
DeGale suffered a shock defeat in December when Truax outpointed him to take the IBF world super-middleweight title from him.
Despite just recovering from a shoulder injury, DeGale rushed back to make the fight – and paid the price, tasting defeat for the second time.
DeGale was granted a re-match and goes agaisnt Truax for a second time, giving him the chance to win back his belt.
He is also hoping a win against the American would give him the chance to fight George Groves for a second time.
What time is the fight?
THIS fight takes place on Sunday, April 8.
The match will be held at the Hard Rock Hotel in Las Vegas.
The pair are expected to walk out at 3am.
Which channel is it on and can I live stream it?
THE fight will be shown on Box Nation in the UK, with coverage starting at 3am.
You can stream the fight on the Box Nation website.
Alternatively, keep up-to-date with all the latest action on the SunSport blog.